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Catalog Number:
16858
CAS Number:
959573-13-8
Boc-3-(Fmoc-aminomethyl)-L-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Phe(3-CH2NHFmoc)-OH, Boc-m-(Fmoc-aminomethyl)-L-Phe-OH, Boc-Phe(3-CH2NHFmoc)-OH
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Product Information

Boc-3-(Fmoc-aminomethyl)-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique combination of protective groups, namely the Boc (tert-butyloxycarbonyl) and Fmoc (9-fluorenylmethoxycarbonyl), which facilitate the selective and efficient assembly of complex peptides. Its robust structure not only enhances stability during synthesis but also allows for easy deprotection, making it an ideal choice for researchers focused on developing therapeutic peptides and biologically active compounds.

In the pharmaceutical industry, Boc-3-(Fmoc-aminomethyl)-L-phenylalanine is particularly valuable for its role in the synthesis of peptide-based drugs, where precision and purity are paramount. Its application extends to the production of peptide libraries for drug discovery, enabling researchers to explore a vast array of potential therapeutic candidates. Additionally, its favorable solubility and compatibility with various coupling reagents make it a preferred choice in solid-phase peptide synthesis, streamlining the process and improving yields.

Synonyms
Boc-L-Phe(3-CH2NHFmoc)-OH, Boc-m-(Fmoc-aminomethyl)-L-Phe-OH, Boc-Phe(3-CH2NHFmoc)-OH
CAS Number
959573-13-8
Purity
≥ 98% (HPLC)
Molecular Formula
C30H32N2O6
Molecular Weight
516.58
MDL Number
MFCD06659131
PubChem ID
53398427
Appearance
White powder
Optical Rotation
[a]D25 = - 14 ± 2 ° (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Phe(3-CH2NHFmoc)-OH, Boc-m-(Fmoc-aminomethyl)-L-Phe-OH, Boc-Phe(3-CH2NHFmoc)-OH
CAS Number
959573-13-8
Purity
≥ 98% (HPLC)
Molecular Formula
C30H32N2O6
Molecular Weight
516.58
MDL Number
MFCD06659131
PubChem ID
53398427
Appearance
White powder
Optical Rotation
[a]D25 = - 14 ± 2 ° (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-3-(Fmoc-aminomethyl)-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for various applications in drug development.
  • Drug Development: Its unique properties enable the development of targeted therapies, particularly in the field of oncology, where specific peptide sequences can enhance drug efficacy.
  • Bioconjugation: The compound is used to attach biomolecules to surfaces or other molecules, facilitating the creation of novel bioconjugates for diagnostics and therapeutic applications.
  • Research in Neuroscience: It plays a role in studying neuropeptides, which are crucial for understanding brain function and developing treatments for neurological disorders.
  • Custom Peptide Libraries: This chemical is essential for generating diverse peptide libraries, aiding researchers in discovering new bioactive compounds and therapeutic candidates.

Citations