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Catalog Number:
16859
CAS Number:
1212895-19-6
Boc-2-(Fmoc-aminomethyl)-D-phenylalanine
Purity:
≥ 98% (HPLC, Chiral purity)
Synonym(s):
Boc-D-Phe(2-CH2NHFmoc)-OH, Boc-2-(Fmoc-aminomethyl)-D-Phe-OH
Documents
$79.22 /100MG
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Product Information

Boc-2-(Fmoc-aminomethyl)-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique combination of protective groups, making it an ideal building block for the synthesis of complex peptides. Its Fmoc (9-fluorenylmethoxycarbonyl) group allows for easy deprotection under mild conditions, facilitating the assembly of peptides with high purity and yield. Researchers and industry professionals appreciate its stability and compatibility with various coupling reagents, enhancing its utility in solid-phase peptide synthesis.

In pharmaceutical research, Boc-2-(Fmoc-aminomethyl)-D-phenylalanine plays a crucial role in the development of peptide-based therapeutics, particularly in designing inhibitors and modulators for various biological targets. Its structural features enable the incorporation of D-amino acids, which can enhance the stability and bioactivity of peptides. This compound is particularly beneficial for those working in medicinal chemistry and biochemistry, offering a reliable option for synthesizing bioactive peptides with potential therapeutic applications.

Synonyms
Boc-D-Phe(2-CH2NHFmoc)-OH, Boc-2-(Fmoc-aminomethyl)-D-Phe-OH
CAS Number
1212895-19-6
Purity
≥ 98% (HPLC, Chiral purity)
Molecular Formula
C30H32N2O6
Molecular Weight
516.58
MDL Number
MFCD06659122
PubChem ID
53398425
Appearance
White to off-white powder
Optical Rotation
[a]D25 = +15 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-D-Phe(2-CH2NHFmoc)-OH, Boc-2-(Fmoc-aminomethyl)-D-Phe-OH
CAS Number
1212895-19-6
Purity
≥ 98% (HPLC, Chiral purity)
Molecular Formula
C30H32N2O6
Molecular Weight
516.58
MDL Number
MFCD06659122
PubChem ID
53398425
Appearance
White to off-white powder
Optical Rotation
[a]D25 = +15 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-2-(Fmoc-aminomethyl)-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, enabling researchers to create complex structures for drug development.
  • Drug Design: It is used in the design of novel pharmaceuticals, particularly in creating targeted therapies that require specific amino acid configurations.
  • Bioconjugation: The compound facilitates bioconjugation processes, allowing for the attachment of biomolecules to drugs, enhancing their efficacy and targeting capabilities.
  • Research in Neuroscience: It plays a role in studying neuropeptides, which are crucial for understanding neurological functions and developing treatments for related disorders.
  • Protein Engineering: This chemical is instrumental in protein engineering applications, where it helps modify proteins for improved stability and functionality in various industrial processes.

Citations