1-Naphthyl-b-D-glucuronide sodium salt is widely utilized in research focused on:
- Drug Metabolism Studies: This compound serves as a substrate for glucuronidation, helping researchers understand how drugs are metabolized in the liver, which is crucial for drug development and safety assessments.
- Biochemical Assays: It is commonly used in enzyme assays to measure the activity of UDP-glucuronosyltransferases (UGTs), which play a significant role in detoxifying drugs and other compounds.
- Pharmacokinetics Research: By studying the absorption, distribution, metabolism, and excretion (ADME) of this compound, researchers can gain insights into the pharmacokinetic profiles of new pharmaceuticals.
- Environmental Toxicology: This chemical is applied in studies assessing the biotransformation of environmental pollutants, aiding in understanding their impact on ecosystems and human health.
- Clinical Research: It is used in studies investigating the role of glucuronidation in drug interactions and personalized medicine, helping to tailor treatments based on individual metabolic profiles.
General Information
Properties
Safety and Regulations
Applications
1-Naphthyl-b-D-glucuronide sodium salt is widely utilized in research focused on:
- Drug Metabolism Studies: This compound serves as a substrate for glucuronidation, helping researchers understand how drugs are metabolized in the liver, which is crucial for drug development and safety assessments.
- Biochemical Assays: It is commonly used in enzyme assays to measure the activity of UDP-glucuronosyltransferases (UGTs), which play a significant role in detoxifying drugs and other compounds.
- Pharmacokinetics Research: By studying the absorption, distribution, metabolism, and excretion (ADME) of this compound, researchers can gain insights into the pharmacokinetic profiles of new pharmaceuticals.
- Environmental Toxicology: This chemical is applied in studies assessing the biotransformation of environmental pollutants, aiding in understanding their impact on ecosystems and human health.
- Clinical Research: It is used in studies investigating the role of glucuronidation in drug interactions and personalized medicine, helping to tailor treatments based on individual metabolic profiles.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
*Catalog Number
*Lot Number
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.