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Catalog Number:
23145
CAS Number:
223593-91-7
sulfo-Succinimidyl-4-hydroxybenzoate
Synonym(s):
sulfo-SHB
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Product Information

Sulfo-Succinimidyl-4-hydroxybenzoate is a versatile chemical compound widely utilized in bioconjugation and labeling applications. This compound features a sulfonic acid group, which enhances its solubility in aqueous solutions, making it particularly valuable for use in biological systems. Its unique structure allows for efficient conjugation with proteins, peptides, and other biomolecules, facilitating the development of targeted therapeutics and diagnostic tools. Researchers often employ sulfo-Succinimidyl-4-hydroxybenzoate in the creation of antibody-drug conjugates, where it serves as a linker to attach cytotoxic agents to antibodies, thereby improving the specificity and efficacy of cancer treatments.

In addition to its applications in drug development, this compound is also instrumental in the field of proteomics, where it aids in the labeling of proteins for mass spectrometry analysis. Its ability to form stable conjugates ensures reliable results in various assays and experiments. The compound's favorable properties, such as its water solubility and reactivity, make it a preferred choice among researchers looking to enhance the performance of their biomolecular studies.

Synonyms
sulfo-SHB
CAS Number
223593-91-7
Molecular Formula
C11H8NO8SNa
Molecular Weight
337.24
MDL Number
MFCD00467961
PubChem ID
44120026
Conditions
Store at 0-8°C
General Information
Synonyms
sulfo-SHB
CAS Number
223593-91-7
Molecular Formula
C11H8NO8SNa
Molecular Weight
337.24
MDL Number
MFCD00467961
PubChem ID
44120026
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

sulfo-Succinimidyl-4-hydroxybenzoate is widely utilized in research focused on:

  • Bioconjugation: This compound is commonly used to link proteins or peptides to other molecules, enhancing their functionality in drug delivery systems.
  • Antibody Labeling: It serves as a useful reagent for labeling antibodies, allowing for better visualization and tracking in various assays.
  • Diagnostic Applications: In the field of diagnostics, it plays a crucial role in developing assays that require stable and specific binding of biomolecules.
  • Protein Purification: The compound aids in the purification of proteins by providing a means to selectively capture target proteins from complex mixtures.
  • Research in Drug Development: It is instrumental in the design of new therapeutics, particularly in the development of targeted therapies that require precise molecular interactions.

Citations