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Catalog Number:
27559
CAS Number:
352-24-9
Ethyl 4,4-difluoroacetoacetate
Purity:
≥ 95% (GC)
Synonym(s):
Ethyl 4,4-difluoro-3-oxobutyrate
Hazmat
Documents
$18.53 /1G
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Product Information

Ethyl 4,4-difluoroacetoacetate is a versatile compound known for its unique fluorinated structure, which enhances its reactivity and stability in various chemical processes. This compound is particularly valuable in the synthesis of pharmaceuticals and agrochemicals, where the presence of fluorine can significantly improve biological activity and metabolic stability. Researchers and industry professionals utilize Ethyl 4,4-difluoroacetoacetate in the development of novel drug candidates, especially in the field of medicinal chemistry, due to its ability to serve as a key intermediate in the synthesis of complex molecules.

Additionally, this compound is recognized for its role in organic synthesis, where it can be employed in the preparation of various fluorinated compounds, offering advantages over non-fluorinated analogs in terms of potency and selectivity. Its unique properties make it an essential tool for chemists looking to innovate in the fields of drug discovery and materials science, providing a pathway to create more effective and targeted solutions.

Synonyms
Ethyl 4,4-difluoro-3-oxobutyrate
CAS Number
352-24-9
Purity
≥ 95% (GC)
Molecular Formula
C6H8F2O3
Molecular Weight
166.12
MDL Number
MFCD00039277
PubChem ID
67697
Density
1.269 g/mL at 25 ºC
Appearance
Colorless to faint yellow clear liquid
Conditions
Store at 0 - 8 °C
Warnings
Warning
General Information
Synonyms
Ethyl 4,4-difluoro-3-oxobutyrate
CAS Number
352-24-9
Purity
≥ 95% (GC)
Molecular Formula
C6H8F2O3
Molecular Weight
166.12
MDL Number
MFCD00039277
PubChem ID
67697
Density
1.269 g/mL at 25 ºC
Appearance
Colorless to faint yellow clear liquid
Conditions
Store at 0 - 8 °C
Warnings
Warning
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
Warning
Applications

Ethyl 4,4-difluoroacetoacetate is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-inflammatory and analgesic drugs.
  • Fluorinated Compounds: It is used in the production of fluorinated compounds, which are valuable in agrochemicals and specialty chemicals, enhancing their efficacy and stability.
  • Organic Synthesis: Researchers leverage its reactivity in organic synthesis to create complex molecules, making it a versatile building block in chemical research.
  • Material Science: The compound finds applications in developing new materials, including polymers and coatings, due to its unique chemical properties that improve durability and performance.
  • Analytical Chemistry: It is employed as a reagent in analytical chemistry for detecting and quantifying various substances, providing precise results in laboratory settings.

Citations