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Catalog Number:
28158
CAS Number:
6559-91-7
4'-Demethylepipodophyllotoxin
Purity:
≥ 99% (HPLC)
Synonym(s):
4'-Dmep
Documents
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Product Information

4'-Demethylepipodophyllotoxin is a naturally occurring lignan derivative known for its significant pharmacological properties. This compound is primarily recognized for its role in cancer research, particularly as a potential chemotherapeutic agent. Its unique structure allows it to inhibit topoisomerase II, an enzyme critical for DNA replication, making it a valuable candidate in the development of anti-cancer therapies. Researchers have explored its efficacy in treating various malignancies, including leukemia and solid tumors, showcasing its potential to enhance the effectiveness of existing treatments.

In addition to its applications in oncology, 4'-Demethylepipodophyllotoxin has been investigated for its anti-inflammatory and antiviral properties, broadening its relevance in pharmaceutical research. Its ability to modulate cellular pathways positions it as a promising lead compound for the development of new therapeutic agents. With ongoing studies, this compound continues to hold potential for innovative applications in both research and clinical settings, making it a valuable addition to any laboratory focused on drug discovery and development.

Synonyms
4'-Dmep
CAS Number
6559-91-7
Purity
≥ 99% (HPLC)
Molecular Formula
C21H20O8
Molecular Weight
400.38
MDL Number
MFCD00189421
PubChem ID
500181
Appearance
White or almost white powder
Conditions
Store at 0-8 °C
General Information
Synonyms
4'-Dmep
CAS Number
6559-91-7
Purity
≥ 99% (HPLC)
Molecular Formula
C21H20O8
Molecular Weight
400.38
MDL Number
MFCD00189421
PubChem ID
500181
Appearance
White or almost white powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4'-Demethylepipodophyllotoxin is widely utilized in research focused on:

  • Cancer Treatment: This compound is a derivative of podophyllotoxin, known for its ability to inhibit cancer cell growth. It is being explored in the development of chemotherapeutic agents, particularly for treating various types of tumors.
  • Antiviral Applications: Research indicates that it may possess antiviral properties, making it a candidate for developing treatments against viral infections, such as HPV, which is linked to cervical cancer.
  • Pharmaceutical Development: The compound serves as a valuable intermediate in synthesizing other medicinal compounds, enhancing the efficiency of drug development processes in the pharmaceutical industry.
  • Natural Product Research: It is used in studies investigating the structural and functional properties of natural products, contributing to the understanding of plant-derived compounds in medicinal chemistry.
  • Biochemical Studies: Researchers utilize it to study its mechanism of action at the molecular level, providing insights into how similar compounds can be optimized for therapeutic use.

Citations