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Catalog Number:
28168
CAS Number:
104706-47-0
(R)-3-Hydroxypyrrolidine hydrochloride
Purity:
≥ 98% (assay)
Synonym(s):
(R)-(-)-3-Pyrrolidinol hydrochloride
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Product Information

(R)-3-Hydroxypyrrolidine hydrochloride is a valuable compound widely utilized in pharmaceutical research and development. This chiral building block is essential for synthesizing various bioactive molecules, particularly in the field of medicinal chemistry. Its unique hydroxyl group enhances its reactivity, making it an ideal candidate for creating complex organic structures. Researchers often leverage (R)-3-Hydroxypyrrolidine hydrochloride in the development of drugs targeting neurological disorders and other therapeutic areas, thanks to its ability to modulate biological pathways effectively.

In addition to its applications in drug synthesis, (R)-3-Hydroxypyrrolidine hydrochloride is recognized for its role in asymmetric synthesis, where it serves as a chiral auxiliary. This property allows chemists to produce enantiomerically pure compounds, which are crucial for ensuring the efficacy and safety of pharmaceutical products. The compound's stability and ease of handling further enhance its appeal in laboratory settings, making it a preferred choice for researchers seeking reliable and efficient reagents for their synthetic endeavors.

Synonyms
(R)-(-)-3-Pyrrolidinol hydrochloride
CAS Number
104706-47-0
Purity
≥ 98% (assay)
Molecular Formula
C4H9NO·HCl
Molecular Weight
123.58
MDL Number
MFCD00191570
PubChem ID
2769408
Melting Point
102 - 107 °C (Lit.)
Appearance
Off-white to yellow or pale brown crystal powder
Optical Rotation
[a]D20 = -7.5 ± 1 ° (C=3.5 in CH3OH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(R)-(-)-3-Pyrrolidinol hydrochloride
CAS Number
104706-47-0
Purity
≥ 98% (assay)
Molecular Formula
C4H9NO·HCl
Molecular Weight
123.58
MDL Number
MFCD00191570
PubChem ID
2769408
Melting Point
102 - 107 °C (Lit.)
Appearance
Off-white to yellow or pale brown crystal powder
Optical Rotation
[a]D20 = -7.5 ± 1 ° (C=3.5 in CH3OH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-3-Hydroxypyrrolidine hydrochloride is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Chiral Catalysis: It is employed as a chiral auxiliary in asymmetric synthesis, helping researchers create enantiomerically pure compounds, which are crucial in drug formulation.
  • Biochemical Research: The compound is used in studies related to neurotransmitter activity, aiding in the understanding of brain chemistry and potential therapeutic targets.
  • Material Science: It finds applications in the development of novel materials, such as polymers, where its unique properties can enhance material performance.
  • Analytical Chemistry: This chemical is utilized in various analytical techniques, including chromatography, to help identify and quantify other compounds in complex mixtures.

Citations