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Catalog Number:
28438
CAS Number:
154229-19-3
Abiraterone
Purity:
≥ 99% (HPLC)
Synonym(s):
17-(3-Pyridyl)androsta-5,16-dien-3β-ol;Androsta-5,16-dien-3-ol
Documents
$51.18 /250MG
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Product Information

Abiraterone is a potent and selective inhibitor of androgen biosynthesis, primarily utilized in the treatment of metastatic castration-resistant prostate cancer (mCRPC). This compound works by blocking the enzyme CYP17A1, which is crucial for the production of androgens, thereby reducing testosterone levels and inhibiting tumor growth. Its unique mechanism of action makes it a vital therapeutic option for patients who have progressed on conventional hormone therapies.

In addition to its primary application in oncology, Abiraterone is also being explored for potential uses in other hormone-sensitive cancers, showcasing its versatility in cancer treatment. Researchers appreciate its ability to improve survival rates and quality of life in patients, making it a significant advancement in cancer therapeutics. With ongoing studies, Abiraterone continues to hold promise for broader applications in the field of oncology, reinforcing its importance in modern cancer treatment protocols.

Synonyms
17-(3-Pyridyl)androsta-5,16-dien-3β-ol;Androsta-5,16-dien-3-ol
CAS Number
154229-19-3
Purity
≥ 99% (HPLC)
Molecular Formula
C24H31NO
Molecular Weight
349.52
MDL Number
MFCD00924100
PubChem ID
21879648
Melting Point
221-235 °C
Appearance
White or off-white solid
Conditions
Store at 0-8°C
General Information
Synonyms
17-(3-Pyridyl)androsta-5,16-dien-3β-ol;Androsta-5,16-dien-3-ol
CAS Number
154229-19-3
Purity
≥ 99% (HPLC)
Molecular Formula
C24H31NO
Molecular Weight
349.52
MDL Number
MFCD00924100
PubChem ID
21879648
Melting Point
221-235 °C
Appearance
White or off-white solid
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Abiraterone is widely utilized in research focused on:

  • Cancer Treatment: Primarily used in the treatment of metastatic castration-resistant prostate cancer, offering patients an effective option to manage their condition when other therapies fail.
  • Hormonal Therapy: Functions as an androgen biosynthesis inhibitor, helping to reduce testosterone levels, which is crucial for the growth of certain prostate cancers.
  • Combination Therapies: Often used in conjunction with other medications to enhance treatment efficacy, providing a multi-faceted approach to cancer management.
  • Clinical Research: Frequently involved in clinical trials aimed at understanding its long-term effects and potential benefits in other hormone-sensitive cancers.
  • Pharmaceutical Development: Plays a significant role in the development of new formulations and delivery methods, improving patient adherence and outcomes.

Citations