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Catalog Number:
28440
CAS Number:
154229-18-2
Abiraterone acetate
Purity:
≥ 99%
Documents
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Product Information

Abiraterone acetate is a potent and selective inhibitor of androgen biosynthesis, primarily utilized in the treatment of metastatic castration-resistant prostate cancer. This compound works by blocking the enzyme CYP17, which is crucial in the production of androgens, thereby reducing testosterone levels and inhibiting tumor growth. Its effectiveness has made it a cornerstone in prostate cancer therapy, particularly for patients who have not responded to conventional hormone therapies.

In addition to its primary use in oncology, Abiraterone acetate is being explored for potential applications in other hormone-sensitive cancers, showcasing its versatility. Researchers appreciate its ability to improve patient outcomes and prolong survival rates, making it a valuable asset in cancer treatment protocols. The compound's unique mechanism of action sets it apart from other therapies, offering a targeted approach that minimizes side effects while maximizing efficacy.

CAS Number
154229-18-2
Purity
≥ 99%
Molecular Formula
C26H33NO2
Molecular Weight
391.55
MDL Number
MFCD00934213
PubChem ID
19961652
Melting Point
144-149 ºC
Appearance
White to off-white powder
Conditions
Store at 0-8°C
General Information
CAS Number
154229-18-2
Purity
≥ 99%
Molecular Formula
C26H33NO2
Molecular Weight
391.55
MDL Number
MFCD00934213
PubChem ID
19961652
Melting Point
144-149 ºC
Appearance
White to off-white powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Abiraterone acetate is widely utilized in research focused on:

  • Prostate Cancer Treatment: This compound is primarily used in the treatment of metastatic castration-resistant prostate cancer, helping to inhibit tumor growth by blocking androgen production.
  • Hormonal Therapy Research: It serves as a crucial tool in studies exploring hormonal therapies, providing insights into how androgen signaling influences cancer progression.
  • Combination Therapy Studies: Researchers often investigate the efficacy of abiraterone acetate in combination with other cancer treatments, enhancing therapeutic outcomes and understanding drug interactions.
  • Pharmacokinetics and Pharmacodynamics: The compound is used in studies to assess its absorption, distribution, metabolism, and excretion, which are vital for optimizing dosing regimens in clinical settings.
  • Biomarker Identification: Abiraterone acetate is employed in research aimed at identifying biomarkers for treatment response, helping to tailor personalized medicine approaches for patients.

Citations