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Catalog Number:
28494
CAS Number:
103750-03-4
5-Maleimidovalericacid -NHS ester
Purity:
≥ 98% (HPLC)
Documents
$106.96 /100MG
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Product Information

5-Maleimidovaleric acid-NHS is a versatile chemical compound widely utilized in bioconjugation and protein labeling applications. This compound features a maleimide group, which allows for selective and stable conjugation to thiol-containing biomolecules, making it an essential tool for researchers in the fields of biochemistry and molecular biology. Its unique structure enhances its reactivity and specificity, enabling the formation of stable thioether bonds with proteins, peptides, and other thiol-containing molecules. This property is particularly beneficial in the development of targeted drug delivery systems and in the creation of bioconjugates for diagnostic applications.

In addition to its use in bioconjugation, 5-Maleimidovaleric acid-NHS is also employed in the synthesis of various biomaterials and in the development of novel therapeutic agents. Its ability to facilitate the attachment of fluorescent tags or drug molecules to proteins opens up new avenues for research in drug discovery and development. Researchers can leverage this compound to enhance the efficacy and specificity of their biomolecular interactions, ultimately leading to advancements in therapeutic strategies and diagnostic tools.

CAS Number
103750-03-4
Purity
≥ 98% (HPLC)
Molecular Formula
C13H14N2O6
Molecular Weight
294.26
MDL Number
MFCD01318603
PubChem ID
10040074
Melting Point
134 - 142 °C
Appearance
White powder
Conditions
Store at 0 - 8 °C
General Information
CAS Number
103750-03-4
Purity
≥ 98% (HPLC)
Molecular Formula
C13H14N2O6
Molecular Weight
294.26
MDL Number
MFCD01318603
PubChem ID
10040074
Melting Point
134 - 142 °C
Appearance
White powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Maleimidovalericacid-NHS is widely utilized in research focused on:

  • Bioconjugation: This chemical is essential for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the development of targeted therapies and diagnostics.
  • Drug Delivery Systems: It plays a critical role in creating advanced drug delivery systems that improve the efficacy and specificity of therapeutic agents, particularly in cancer treatment.
  • Protein Labeling: Researchers use it for labeling proteins with fluorescent tags, facilitating the study of protein interactions and dynamics in live cells.
  • Diagnostic Assays: The compound is integral in the design of sensitive diagnostic assays, such as ELISA, where it helps in the detection of specific biomarkers in clinical samples.
  • Material Science: It is also applied in the modification of materials for biomedical applications, improving biocompatibility and functionality of implants and prosthetics.

Citations