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Catalog Number:
28509
CAS Number:
25137-00-2
R-(-)-Nipecotic acid
Purity:
≥ 98% (assay by titration)
Synonym(s):
(R-(-)-3-Piperidinecarboxylic acid
Documents
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Product Information

(R)-(-)-nipecotic acid is a chiral compound recognized for its significant role in the field of medicinal chemistry. This compound, also known as (3R)-piperidine-3-carboxylic acid, exhibits unique properties that make it valuable in the synthesis of various pharmaceuticals, particularly in the development of neuroactive agents. Its structural characteristics allow it to interact effectively with neurotransmitter systems, making it a candidate for research into treatments for neurological disorders such as epilepsy and anxiety.

In addition to its medicinal applications, (R)-(-)-nipecotic acid serves as an important building block in organic synthesis, facilitating the creation of more complex molecules. Researchers appreciate its ability to enhance the efficacy of certain drugs while minimizing side effects, thus holding promise for the development of safer therapeutic options. With its versatile applications in both research and industry, (R)-(-)-nipecotic acid stands out as a compound of interest for professionals seeking innovative solutions in drug development and synthesis.

Synonyms
(R-(-)-3-Piperidinecarboxylic acid
CAS Number
25137-00-2
Purity
≥ 98% (assay by titration)
Molecular Formula
C6H11NO2
Molecular Weight
129.16
MDL Number
MFCD01630787
PubChem ID
4498
Appearance
White crystalline solid
Optical Rotation
[a]D20 =- 4 ± 2 º (C=5 in H2O)
Conditions
Store at 0-8°C
General Information
Synonyms
(R-(-)-3-Piperidinecarboxylic acid
CAS Number
25137-00-2
Purity
≥ 98% (assay by titration)
Molecular Formula
C6H11NO2
Molecular Weight
129.16
MDL Number
MFCD01630787
PubChem ID
4498
Appearance
White crystalline solid
Optical Rotation
[a]D20 =- 4 ± 2 º (C=5 in H2O)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(-)-nipecotic acid is widely utilized in research focused on

  • Neuroscience Research: This compound is studied for its potential neuroprotective effects and its role as a GABA uptake inhibitor, making it valuable for understanding neurological disorders.
  • Pharmaceutical Development: It serves as a key intermediate in the synthesis of various pharmaceuticals, particularly those targeting the central nervous system, enhancing drug efficacy.
  • Analytical Chemistry: Used as a standard in chromatographic techniques, it aids in the accurate quantification of related compounds in biological samples.
  • Behavioral Studies: Researchers utilize it to investigate its effects on behavior in animal models, providing insights into anxiety and depression treatments.
  • Biochemical Applications: Its role in studying neurotransmitter systems helps in the development of new therapeutic strategies for mental health disorders.

Citations