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Catalog Number:
29621
CAS Number:
78654-82-7
Boc-L-2,5,7-tri-tert-butyl-tryptophan
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Tbt-OH
Documents
$127.79 /100MG
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Product Information

Boc-L-2,5,7-tri-tert-butyl-tryptophan is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is characterized by its unique structure, featuring three tert-butyl groups that enhance its lipophilicity and stability, making it an excellent candidate for various applications in medicinal chemistry. Researchers often utilize Boc-L-2,5,7-tri-tert-butyl-tryptophan in the design of bioactive peptides, particularly in studies focused on neuropharmacology and cancer research. Its protective Boc (tert-butyloxycarbonyl) group allows for selective deprotection, facilitating the synthesis of complex peptide structures.

In addition to its applications in peptide synthesis, Boc-L-2,5,7-tri-tert-butyl-tryptophan is also valuable in the development of pharmaceuticals that target specific biological pathways. Its enhanced stability and solubility compared to other tryptophan derivatives make it a preferred choice for researchers aiming to create potent therapeutic agents. This compound not only streamlines the synthesis process but also improves the overall efficacy of the resulting peptides, making it an essential tool for professionals in the pharmaceutical and biotechnology industries.

Synonyms
Boc-L-Tbt-OH
CAS Number
78654-82-7
Purity
≥ 98% (HPLC)
Molecular Formula
C28H44N2O4
Molecular Weight
472.67
MDL Number
MFCD18782817
PubChem ID
13174962
Appearance
White solid
Optical Rotation
[a]20D = +16 ± 2 º (C=1 in DMF) or [a]20D = +42 ± 2 º (C=1 in CH2Cl2)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Tbt-OH
CAS Number
78654-82-7
Purity
≥ 98% (HPLC)
Molecular Formula
C28H44N2O4
Molecular Weight
472.67
MDL Number
MFCD18782817
PubChem ID
13174962
Appearance
White solid
Optical Rotation
[a]20D = +16 ± 2 º (C=1 in DMF) or [a]20D = +42 ± 2 º (C=1 in CH2Cl2)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-2,5,7-tri-tert-butyl-tryptophan is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in pharmaceutical research where specific amino acid sequences are crucial for drug development.
  • Drug Formulation: Its unique structure enhances the stability and solubility of drug formulations, making it advantageous in the development of oral medications that require improved bioavailability.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach biomolecules to drugs or imaging agents, which is essential in targeted therapy and diagnostics.
  • Research in Neuroscience: Due to its tryptophan derivative nature, it plays a role in studies related to neurotransmitter synthesis and can aid in understanding mood disorders and neuropharmacology.
  • Cosmetic Applications: Its properties are explored in the cosmetic industry for formulating products that require amino acids for skin health, leveraging its stability and effectiveness in formulations.

Citations