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Catalog Number:
29765
CAS Number:
1408057-39-5
4,4-Difluoro-D-Proline methyl ester hydrochloride
Synonym(s):
(R-methyl 4,4-difluoropyrrolidine-2-carboxylate hydrochloride
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$260.69 /100MG
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Product Information

4,4-Difluoro-D-Proline methyl ester hydrochloride is a specialized amino acid derivative that has garnered attention in pharmaceutical and biochemical research. This compound is recognized for its unique fluorinated structure, which enhances its stability and bioactivity compared to non-fluorinated analogs. Researchers utilize 4,4-Difluoro-D-Proline methyl ester hydrochloride in the synthesis of peptides and as a building block in drug discovery, particularly in the development of therapeutics targeting neurological disorders. Its ability to mimic natural amino acids while providing distinct chemical properties makes it an invaluable tool in medicinal chemistry.

In addition to its applications in drug development, this compound is also employed in the study of protein folding and structure due to its influence on peptide conformation. The incorporation of fluorine into the proline structure can lead to improved binding affinities and altered pharmacokinetics, making it a promising candidate for further exploration in various therapeutic areas. With its unique properties and versatile applications, 4,4-Difluoro-D-Proline methyl ester hydrochloride stands out as a significant compound for researchers and industry professionals alike.

Synonyms
(R-methyl 4,4-difluoropyrrolidine-2-carboxylate hydrochloride
CAS Number
1408057-39-5
Molecular Formula
C6H10ClF2NO2
Molecular Weight
201.59
MDL Number
MFCD23106099
PubChem ID
71742469
Conditions
Store at 0-8 ºC
General Information
Synonyms
(R-methyl 4,4-difluoropyrrolidine-2-carboxylate hydrochloride
CAS Number
1408057-39-5
Molecular Formula
C6H10ClF2NO2
Molecular Weight
201.59
MDL Number
MFCD23106099
PubChem ID
71742469
Conditions
Store at 0-8 ºC
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4,4-Difluoro-D-Proline methyl ester hydrochloride is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Peptide Synthesis: It is commonly used in peptide synthesis due to its ability to introduce fluorinated amino acids, which can enhance the stability and bioactivity of peptides.
  • Biochemical Research: Researchers leverage this compound to study protein interactions and enzyme functions, as the fluorine atoms can influence molecular behavior and binding affinities.
  • Material Science: Its unique properties make it valuable in the development of advanced materials, such as coatings and polymers that require specific chemical resistance.
  • Analytical Chemistry: The compound is utilized in various analytical techniques, including NMR and mass spectrometry, to improve the detection and characterization of complex mixtures.

Citations