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Catalog Number:
29766
CAS Number:
156046-05-8
4,4-Difluoro-L-Proline methyl ester hydrochloride
Synonym(s):
(S-methyl 4,4-difluoropyrrolidine-2-carboxylate hydrochloride
Documents
$208.31 /100MG
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Product Information

4,4-Difluoro-L-Proline methyl ester hydrochloride is a specialized amino acid derivative that has garnered attention in the fields of medicinal chemistry and pharmaceutical research. This compound is recognized for its unique structural features, including the presence of two fluorine atoms, which enhance its biological activity and stability. Researchers have utilized 4,4-Difluoro-L-Proline methyl ester hydrochloride in the synthesis of various bioactive molecules, particularly in the development of peptide-based therapeutics. Its ability to mimic natural amino acids while providing distinct properties makes it an invaluable tool for drug design and development.

In addition to its applications in drug discovery, this compound has shown promise in the study of protein folding and enzyme activity, offering insights into complex biological processes. The incorporation of fluorinated amino acids like 4,4-Difluoro-L-Proline methyl ester hydrochloride can lead to improved pharmacokinetic profiles, making it a preferred choice for researchers aiming to enhance the efficacy of their compounds. With its versatile applications and significant advantages over traditional amino acids, this compound is essential for advancing research in medicinal chemistry and related fields.

Synonyms
(S-methyl 4,4-difluoropyrrolidine-2-carboxylate hydrochloride
CAS Number
156046-05-8
Molecular Formula
C6H10ClF2NO2
Molecular Weight
201.59
MDL Number
MFCD23106100
PubChem ID
71742469
Conditions
Store at 0-8 ºC
General Information
Synonyms
(S-methyl 4,4-difluoropyrrolidine-2-carboxylate hydrochloride
CAS Number
156046-05-8
Molecular Formula
C6H10ClF2NO2
Molecular Weight
201.59
MDL Number
MFCD23106100
PubChem ID
71742469
Conditions
Store at 0-8 ºC
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4,4-Difluoro-L-Proline methyl ester hydrochloride is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a building block in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders due to its unique fluorinated structure that enhances bioactivity.
  • Peptide Synthesis: It is employed in the synthesis of peptides, providing researchers with a means to introduce fluorinated amino acids, which can improve the stability and efficacy of peptide-based therapeutics.
  • Biochemical Research: The compound is used in studies investigating protein folding and stability, as the incorporation of fluorinated residues can significantly affect the properties of proteins, aiding in the understanding of their functions.
  • Material Science: In the field of materials, it is explored for creating novel polymers with enhanced thermal and chemical resistance, making it valuable for applications in coatings and advanced materials.
  • Drug Delivery Systems: Its unique properties allow for the development of advanced drug delivery systems that can improve the targeting and release profiles of therapeutic agents, addressing challenges in current drug delivery methods.

Citations