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Catalog Number:
30487
CAS Number:
291529-78-7
Nβ-Fmoc-L-2,3-diaminopropionic acid tert-butyl ester hydrochloride
Purity:
≥ 99% (HPLC, TLC)
Synonym(s):
H-L-Dap(Fmoc)-OtBu·HCl
Documents
$72.20 /100MG
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Product Information

Nb-Fmoc-L-2,3-diaminopropionic acid tert-butyl ester hydrochloride is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is essential for the selective protection of amino groups during the synthesis of complex peptides. Its tert-butyl ester form enhances solubility and stability, making it an ideal choice for researchers working with sensitive biological molecules.

In practical applications, Nb-Fmoc-L-2,3-diaminopropionic acid tert-butyl ester hydrochloride is particularly valuable in the development of peptide-based therapeutics, where precise control over amino acid sequences is crucial. Its unique structure allows for the introduction of diamino functionalities, which can lead to the creation of novel peptides with enhanced biological activity. This compound is also beneficial in the field of drug discovery, where it can facilitate the design of inhibitors or modulators for various biological targets. Researchers will appreciate its ease of use and the efficiency it brings to synthetic processes, making it a preferred choice in laboratories focused on peptide chemistry.

Synonyms
H-L-Dap(Fmoc)-OtBu·HCl
CAS Number
291529-78-7
Purity
≥ 99% (HPLC, TLC)
Molecular Formula
C22H27ClN2O4
Molecular Weight
418.9
MDL Number
MFCD21363203
PubChem ID
118389404
Melting Point
> 169 °C (dec.)
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -8 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
H-L-Dap(Fmoc)-OtBu·HCl
CAS Number
291529-78-7
Purity
≥ 99% (HPLC, TLC)
Molecular Formula
C22H27ClN2O4
Molecular Weight
418.9
MDL Number
MFCD21363203
PubChem ID
118389404
Melting Point
> 169 °C (dec.)
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -8 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nb-Fmoc-L-2,3-diaminopropionic acid tert-butyl ester hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the efficiency and yield of desired products.
  • Drug Development: It plays a crucial role in the development of pharmaceutical compounds, particularly in designing drugs that target specific biological pathways, thanks to its unique structural properties.
  • Bioconjugation: The chemical is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is essential in creating targeted therapies and diagnostics.
  • Research in Neuroscience: It is utilized in studies related to neurotransmitter systems, aiding in the development of compounds that can modulate neural activity, which is vital for understanding various neurological disorders.
  • Material Science: This compound finds applications in the development of novel materials, particularly those that require specific functional groups for enhanced performance in various applications.

Citations