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Catalog Number:
31504
CAS Number:
2524-64-3
Diphenyl phosphoryl chloride
Purity:
≥ 99%(T, GC)
Synonym(s):
Diphenyl phosphorochloridate, Diphenyl Chlorophosphate
Hazmat
Documents
$20.00 /25G
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Product Information

Diphenyl phosphoryl chloride is a versatile chemical compound widely utilized in organic synthesis and pharmaceutical research. This compound serves as an effective phosphorylating agent, enabling the introduction of phosphate groups into various organic molecules. Its unique reactivity allows for the formation of phosphonate esters, which are crucial intermediates in the synthesis of biologically active compounds, including pharmaceuticals and agrochemicals. Researchers appreciate its ability to facilitate the development of complex molecular architectures, making it a valuable tool in medicinal chemistry and drug discovery.

In addition to its applications in synthesis, Diphenyl phosphoryl chloride is also employed in the preparation of phosphonylated derivatives, which have shown promise in enhancing the efficacy of certain therapeutic agents. Its stability and ease of handling further contribute to its appeal in laboratory settings. With its broad range of applications, Diphenyl phosphoryl chloride stands out as an essential reagent for chemists looking to innovate and streamline their synthetic processes.

Synonyms
Diphenyl phosphorochloridate, Diphenyl Chlorophosphate
CAS Number
2524-64-3
Purity
≥ 99%(T, GC)
Molecular Formula
C12H10ClO3P
Molecular Weight
268.64
MDL Number
MFCD00003030
PubChem ID
75654
Density
1.296
Appearance
Colorless to light yellow clear liquid
Boiling Point
314-316 °C / 272 mmHg
Refractive Index
1.55
Conditions
Store at RT
General Information
Synonyms
Diphenyl phosphorochloridate, Diphenyl Chlorophosphate
CAS Number
2524-64-3
Purity
≥ 99%(T, GC)
Molecular Formula
C12H10ClO3P
Molecular Weight
268.64
MDL Number
MFCD00003030
PubChem ID
75654
Density
1.296
Appearance
Colorless to light yellow clear liquid
Boiling Point
314-316 °C / 272 mmHg
Refractive Index
1.55
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Diphenyl phosphoryl chloride is widely utilized in research focused on:

  • Synthesis of Phosphoryl Compounds: It serves as a key reagent in the synthesis of various phosphoryl compounds, which are essential in developing pharmaceuticals and agrochemicals.
  • Protein Modification: This chemical is used to modify proteins, enhancing their stability and activity, making it valuable in biochemistry and molecular biology research.
  • Development of Pesticides: It plays a crucial role in the formulation of certain pesticides, providing effective solutions for crop protection in agriculture.
  • Organic Synthesis: Diphenyl phosphoryl chloride is employed in organic synthesis as a chlorinating agent, facilitating the introduction of phosphorus into organic molecules.
  • Analytical Chemistry: It is used in analytical methods to detect and quantify phosphorous-containing compounds, aiding researchers in environmental and materials science.

Citations