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Catalog Number:
31520
CAS Number:
4648-54-8
Azidotrimethylsilane
Purity:
≥ 97% (GC)
Synonym(s):
Trimethylsilyl azide
Hazmat
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Product Information

Azidotrimethylsilane is a versatile organosilicon compound known for its unique azido functional group, which enhances its reactivity in various chemical applications. This compound is particularly valuable in organic synthesis, where it serves as a key reagent for the introduction of azide groups into organic molecules. Its ability to act as a silicon-based source of azide makes it an essential tool in click chemistry, facilitating the formation of stable linkages in the development of pharmaceuticals, polymers, and advanced materials. Researchers appreciate its utility in the preparation of functionalized silanes and its role in the synthesis of complex organic compounds, which can lead to innovative solutions in drug discovery and materials science.

Moreover, azidotrimethylsilane exhibits favorable properties such as high stability and ease of handling, making it an attractive choice for both laboratory and industrial applications. Its compatibility with various reaction conditions allows for flexibility in synthetic pathways, enabling chemists to explore new methodologies in their research. With its growing importance in the field of synthetic chemistry, azidotrimethylsilane stands out as a compound that not only enhances reaction efficiency but also opens new avenues for exploration in chemical innovation.

Synonyms
Trimethylsilyl azide
CAS Number
4648-54-8
Purity
≥ 97% (GC)
Molecular Formula
C3H9N3Si
Molecular Weight
115.21
MDL Number
MFCD00001986
PubChem ID
78378
Melting Point
- 95 °C
Density
0.868
Appearance
Colorless to light yellow liquid
Boiling Point
95 - 97 °C
Refractive Index
1.414
Conditions
Store at 2-8 °C
General Information
Synonyms
Trimethylsilyl azide
CAS Number
4648-54-8
Purity
≥ 97% (GC)
Molecular Formula
C3H9N3Si
Molecular Weight
115.21
MDL Number
MFCD00001986
PubChem ID
78378
Melting Point
- 95 °C
Density
0.868
Appearance
Colorless to light yellow liquid
Boiling Point
95 - 97 °C
Refractive Index
1.414
Conditions
Store at 2-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Azidotrimethylsilane is widely utilized in research focused on:

  • Synthetic Chemistry: It serves as a versatile reagent for the introduction of azide groups in organic synthesis, facilitating the creation of complex molecules.
  • Click Chemistry: This compound is a key player in click chemistry reactions, allowing for efficient and selective coupling of azides with alkynes, which is crucial in drug development and materials science.
  • Polymer Science: Azidotrimethylsilane can be used to modify polymers, enhancing their properties for applications in coatings, adhesives, and sealants.
  • Bioconjugation: It is employed in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in the development of biosensors and targeted drug delivery systems.
  • Materials Development: The compound's unique properties make it valuable in the development of novel materials, such as photonic devices and nanomaterials, providing advantages in performance and functionality.

Citations