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Catalog Number:
31647
CAS Number:
91574-36-6
3-(Maleimidomethyl)-benzoic acid-NHS ester
Synonym(s):
2,5-dioxopyrrolidin-1-yl 3-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)benzoate, 3-Mal-MBz-NHS
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$143.62 /100MG
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Product Information

3-(Maleimidomethyl)-benzoic acid-NHS ester is a versatile compound widely utilized in bioconjugation and protein labeling applications. This NHS ester derivative is particularly valuable for researchers in the fields of biochemistry and molecular biology, as it facilitates the formation of stable covalent bonds with amine-containing biomolecules. Its unique maleimide functionality allows for selective conjugation to thiol groups, making it an ideal choice for creating targeted drug delivery systems and diagnostic agents.

This compound is especially beneficial in the development of antibody-drug conjugates (ADCs) and other therapeutic modalities, where precise targeting is crucial for efficacy and safety. Additionally, its ease of use and compatibility with various biological systems make it a preferred choice for scientists looking to enhance their research in proteomics and biomolecular interactions. With its ability to improve the specificity and stability of conjugated products, 3-(Maleimidomethyl)-benzoic acid-NHS ester stands out as a key reagent in advancing innovative therapeutic strategies.

Synonyms
2,5-dioxopyrrolidin-1-yl 3-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)benzoate, 3-Mal-MBz-NHS
CAS Number
91574-36-6
Molecular Formula
C16H12N2O6
Molecular Weight
328.28
MDL Number
MFCD28126945
PubChem ID
13421302
Conditions
Store at ≤ -4 °C
General Information
Synonyms
2,5-dioxopyrrolidin-1-yl 3-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)benzoate, 3-Mal-MBz-NHS
CAS Number
91574-36-6
Molecular Formula
C16H12N2O6
Molecular Weight
328.28
MDL Number
MFCD28126945
PubChem ID
13421302
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-(Maleimidomethyl)-benzoic acid-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for attaching biomolecules, such as proteins and peptides, to surfaces or other molecules, enhancing the development of targeted drug delivery systems.
  • Diagnostic Applications: It plays a crucial role in the creation of diagnostic agents, allowing for the labeling of antibodies and other proteins used in imaging techniques, which improves disease detection.
  • Protein Labeling: Researchers use this ester for site-specific labeling of proteins, facilitating studies on protein interactions and functions, which is vital in understanding cellular processes.
  • Therapeutic Development: It aids in the design of novel therapeutics by enabling the conjugation of drugs to antibodies, enhancing their efficacy and specificity in targeting disease cells.
  • Research in Material Science: The compound is also applied in the development of advanced materials, where it helps in modifying surfaces for better adhesion and functionality in various industrial applications.

Citations