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Catalog Number:
31696
CAS Number:
1202179-60-9
Fmoc-L-Arg(Pbf)-O-CH2-Ph-OCH2-CH2-COOH
Purity:
≥ 99.5% (Chiral HPLC)
Documents
$72.31 /1G
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Product Information

Fmoc-L-Arg(Pbf)-O-CH2-Ph-OCH2-CH2-COOH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc group, which is essential for the selective deprotection of amino acids during solid-phase peptide synthesis (SPPS). Its unique structure, including the Pbf (2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl) sulfonamide moiety, enhances the stability and solubility of peptides, making it an excellent choice for researchers aiming to develop complex peptide-based therapeutics.

In addition to its role in SPPS, this compound can be employed in the synthesis of bioactive peptides, which are crucial in various fields such as pharmaceuticals, biotechnology, and molecular biology. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of sensitive functional groups makes it a valuable tool for chemists and biochemists. Researchers can leverage Fmoc-L-Arg(Pbf)-O-CH2-Ph-OCH2-CH2-COOH to create innovative peptide sequences that may lead to breakthroughs in drug discovery and development.

CAS Number
1202179-60-9
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C44H50N4O10S
Molecular Weight
826.96
MDL Number
MFCD08457844
Appearance
White powder
Optical Rotation
[a]20D = -4 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
CAS Number
1202179-60-9
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C44H50N4O10S
Molecular Weight
826.96
MDL Number
MFCD08457844
Appearance
White powder
Optical Rotation
[a]20D = -4 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-Arg(Pbf)-O-CH2-Ph-OCH2-CH2-COOH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the efficient assembly of complex peptide sequences.
  • Drug Development: It is used in the design of peptide-based therapeutics, where its unique structure can enhance the stability and bioavailability of drug candidates.
  • Bioconjugation: The chemical is valuable in bioconjugation processes, facilitating the attachment of peptides to various biomolecules, which is crucial for developing targeted drug delivery systems.
  • Research in Molecular Biology: Researchers utilize this compound to study protein interactions and functions, as it can be incorporated into proteins to modify their properties for experimental purposes.
  • Diagnostics: Its applications extend to the development of diagnostic tools, where it can be used to create peptide-based assays for detecting specific biomarkers in clinical samples.

Citations