Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
31951
CAS Number:
359766-58-8
Fmoc-β-tert-butyl-D-alanine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-β-tBu-D-Ala-OH, Fmoc-D-Neopentylglycine
Documents
$110.70 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-b-tert-butyl-D-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which facilitates the selective modification of amino acids during solid-phase peptide synthesis. Its tert-butyl side chain enhances solubility and stability, making it an ideal choice for researchers aiming to create complex peptides with improved yields and purity.

In the pharmaceutical industry, Fmoc-b-tert-butyl-D-alanine plays a crucial role in the development of therapeutic peptides, particularly those targeting specific biological pathways. Its unique structure allows for the incorporation of D-amino acids, which can enhance the bioactivity and stability of the resulting peptides. This compound is particularly beneficial in the synthesis of cyclic peptides and peptidomimetics, offering researchers a reliable tool for advancing drug discovery and development.

Synonyms
Fmoc-β-tBu-D-Ala-OH, Fmoc-D-Neopentylglycine
CAS Number
359766-58-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C22H25NO4
Molecular Weight
367.44
MDL Number
MFCD01861369
PubChem ID
4712553
Appearance
White to off-white powder/solid
Optical Rotation
[a]D20 = 17 ± 5 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-β-tBu-D-Ala-OH, Fmoc-D-Neopentylglycine
CAS Number
359766-58-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C22H25NO4
Molecular Weight
367.44
MDL Number
MFCD01861369
PubChem ID
4712553
Appearance
White to off-white powder/solid
Optical Rotation
[a]D20 = 17 ± 5 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-b-tert-butyl-D-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for amino acids in solid-phase peptide synthesis, enhancing the efficiency and yield of peptide formation.
  • Drug Development: It plays a crucial role in the design of peptide-based therapeutics, particularly in the development of drugs targeting specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing for the attachment of peptides to other biomolecules, which is essential in creating targeted drug delivery systems.
  • Research in Neuroscience: It is utilized in studies involving neuropeptides, aiding in the understanding of their roles in brain function and potential therapeutic applications.
  • Custom Peptide Libraries: Researchers use it to create diverse peptide libraries for screening potential drug candidates, facilitating the discovery of new therapeutic agents.

Citations