Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
31969
CAS Number:
1421258-67-4
Fmoc-D-β-homoglutamic acid 6-tert-butyl ester
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-β-HomoGlu(OtBu)-OH, (R-3-(Fmoc-amino)adipic acid 6-tert-butyl ester
Documents
$79.22 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-D-b-homoglutamic acid 6-tert-butyl ester is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is crucial for the selective protection of amine functionalities during the synthesis process. Its unique structure allows for the efficient incorporation of D-homoglutamic acid into peptides, enhancing their stability and bioactivity. Researchers and industry professionals appreciate its role in the development of therapeutics, particularly in the fields of oncology and neurology, where peptide-based drugs are gaining traction.

The tert-butyl ester group further enhances the compound's solubility and stability, making it an ideal choice for various applications in organic synthesis and medicinal chemistry. Its ability to facilitate the formation of complex peptide structures while maintaining high yields makes it a preferred option for researchers looking to optimize their synthesis protocols. With its robust performance and reliability, Fmoc-D-b-homoglutamic acid 6-tert-butyl ester stands out as a valuable tool in the arsenal of peptide chemists and pharmaceutical developers.

Synonyms
Fmoc-D-β-HomoGlu(OtBu)-OH, (R-3-(Fmoc-amino)adipic acid 6-tert-butyl ester
CAS Number
1421258-67-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C25H29NO6
Molecular Weight
439.51
MDL Number
MFCD22887410
PubChem ID
4283598
Appearance
White solid
Optical Rotation
[a]20D = 11 ± 2 ° (C=1 in CHCl3)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-β-HomoGlu(OtBu)-OH, (R-3-(Fmoc-amino)adipic acid 6-tert-butyl ester
CAS Number
1421258-67-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C25H29NO6
Molecular Weight
439.51
MDL Number
MFCD22887410
PubChem ID
4283598
Appearance
White solid
Optical Rotation
[a]20D = 11 ± 2 ° (C=1 in CHCl3)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-b-homoglutamic acid 6-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Its unique structure aids in the design of novel pharmaceutical compounds, particularly in the development of drugs targeting neurological disorders.
  • Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted therapies.
  • Research in Neuroscience: It plays a role in studies related to neurotransmitter function, helping researchers understand the biochemical pathways involved in brain activity.
  • Polymer Chemistry: The compound is also applied in the synthesis of functionalized polymers, which can be used in various applications including drug delivery systems and biomaterials.

Citations