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Catalog Number:
37211
CAS Number:
2251-50-5
2,3,4,5,6-Pentafluorobenzoyl chloride
Purity:
≥ 99% (GC)
Synonym(s):
Pentafluorobenzoic acid chloride, Perfluorobenzoyl chloride
Hazmat
Documents
$22.03 /5G
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Product Information

2,3,4,5,6-Pentafluorobenzoyl chloride is a highly fluorinated aromatic compound known for its unique reactivity and versatility in various chemical applications. This compound features five fluorine atoms attached to a benzoyl chloride structure, making it an excellent reagent for synthesizing fluorinated organic compounds. Its strong electrophilic nature allows it to participate in nucleophilic substitution reactions, which are essential in the development of pharmaceuticals, agrochemicals, and advanced materials. Researchers and industry professionals can leverage 2,3,4,5,6-Pentafluorobenzoyl chloride to create novel fluorinated derivatives that exhibit enhanced biological activity and improved material properties.

In addition to its synthetic utility, this compound is particularly valuable in the field of medicinal chemistry, where fluorination can significantly influence the pharmacokinetic properties of drug candidates. Its application in the production of fluorinated polymers and specialty chemicals further highlights its importance in modern chemical research and industrial processes. With its unique properties and broad applicability, 2,3,4,5,6-Pentafluorobenzoyl chloride stands out as a crucial tool for chemists aiming to innovate and enhance their product offerings.

Synonyms
Pentafluorobenzoic acid chloride, Perfluorobenzoyl chloride
CAS Number
2251-50-5
Purity
≥ 99% (GC)
Molecular Formula
C7ClF5O
Molecular Weight
230.52
MDL Number
MFCD00000657
PubChem ID
75256
Density
1.668
Appearance
Clear colorless liquid
Boiling Point
158 - 159 °C
Refractive Index
1.453
Conditions
Store at RT
General Information
Synonyms
Pentafluorobenzoic acid chloride, Perfluorobenzoyl chloride
CAS Number
2251-50-5
Purity
≥ 99% (GC)
Molecular Formula
C7ClF5O
Molecular Weight
230.52
MDL Number
MFCD00000657
PubChem ID
75256
Density
1.668
Appearance
Clear colorless liquid
Boiling Point
158 - 159 °C
Refractive Index
1.453
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,3,4,5,6-Pentafluorobenzoyl chloride is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in creating fluorinated drug candidates that can enhance bioactivity and selectivity.
  • Polymer Chemistry: It is used in the production of fluorinated polymers, which are known for their chemical resistance and thermal stability, making them ideal for applications in coatings and high-performance materials.
  • Analytical Chemistry: This chemical acts as a derivatizing agent in analytical methods, improving the detection and quantification of compounds in complex mixtures through enhanced chromatographic properties.
  • Fluorinated Compounds Synthesis: It plays a significant role in the synthesis of various fluorinated compounds, which are valuable in agrochemicals and specialty chemicals, providing unique properties like increased potency and reduced environmental impact.
  • Research in Material Science: The compound is utilized in developing advanced materials with tailored properties, such as increased hydrophobicity and improved electrical conductivity, beneficial for electronic and energy applications.

Citations