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Catalog Number:
37334
CAS Number:
54925-64-3
1-(tert-Butyldimethylsilyl)imidazole
Purity:
≥ 98% (Assay by titration)
Synonym(s):
TBDMSIM, TBSIM
Documents
$58.39 /1G
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Product Information

1-(tert-Butyldimethylsilyl)imidazole is a versatile organosilicon compound known for its unique properties that make it valuable in various chemical applications. This compound serves as an effective protecting group for amines and alcohols in organic synthesis, facilitating the selective functionalization of complex molecules. Its stability under a range of reaction conditions allows researchers to utilize it in diverse synthetic pathways, including peptide synthesis and the development of pharmaceuticals. Additionally, its ability to enhance solubility and reactivity makes it a preferred choice in catalysis and material science, particularly in the formulation of advanced materials and coatings.

The compound's distinctive structure, featuring a tert-butyldimethylsilyl group, provides significant advantages over similar compounds by improving the stability and reactivity of intermediates in synthetic routes. This makes 1-(tert-Butyldimethylsilyl)imidazole an essential tool for chemists looking to streamline their processes and achieve higher yields. Its applications extend to the development of novel catalysts and the synthesis of complex organic molecules, making it a valuable addition to any research or industrial laboratory focused on innovative chemical solutions.

Synonyms
TBDMSIM, TBSIM
CAS Number
54925-64-3
Purity
≥ 98% (Assay by titration)
Molecular Formula
C9H18N2Si
Molecular Weight
182.34
MDL Number
MFCD00011682
PubChem ID
171385
Density
0.940
Appearance
Clear colorless liquid
Boiling Point
52 - 53 °C / 0.2 mmHg
Refractive Index
1.480
Conditions
Store at RT
General Information
Synonyms
TBDMSIM, TBSIM
CAS Number
54925-64-3
Purity
≥ 98% (Assay by titration)
Molecular Formula
C9H18N2Si
Molecular Weight
182.34
MDL Number
MFCD00011682
PubChem ID
171385
Density
0.940
Appearance
Clear colorless liquid
Boiling Point
52 - 53 °C / 0.2 mmHg
Refractive Index
1.480
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1-(tert-Butyldimethylsilyl)imidazole is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a protecting group in organic synthesis, allowing chemists to selectively modify other functional groups without interference.
  • Catalysis: It acts as a catalyst in various chemical reactions, enhancing reaction rates and improving yields, particularly in the synthesis of complex organic molecules.
  • Pharmaceutical Development: The compound is used in drug formulation processes, where its unique properties help stabilize active pharmaceutical ingredients, improving their efficacy and shelf life.
  • Material Science: It is applied in the development of advanced materials, including coatings and polymers, where its silane functionality contributes to enhanced durability and performance.
  • Analytical Chemistry: Researchers utilize it in chromatography and other analytical techniques to improve separation and detection of compounds, making it easier to analyze complex mixtures.

Citations