🌟 99% Happy customers

📦 Same-day shipping on in-stock items

Catalog Number:
37714
CAS Number:
38821-49-7
Carbidopa monohydrate
Purity:
≥ 98% (Assay, HPLC)
Synonym(s):
(S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropionic acid monohydrate
Documents
$26.44 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Carbidopa monohydrate is a vital pharmaceutical compound primarily utilized in the treatment of Parkinson's disease. By inhibiting the enzyme aromatic L-amino acid decarboxylase, it prevents the premature conversion of levodopa to dopamine outside the brain, thereby enhancing the efficacy of levodopa therapy. This synergistic effect allows for lower doses of levodopa, minimizing side effects while maximizing therapeutic benefits. Carbidopa monohydrate is especially beneficial in combination therapies, where it improves the overall management of Parkinson's symptoms and enhances patient quality of life.

In addition to its primary use in neurology, Carbidopa monohydrate is also being explored for potential applications in other areas of medicine, including its role in enhancing the bioavailability of certain drugs. Its unique properties make it a valuable asset in both clinical and research settings, providing a reliable option for healthcare professionals seeking effective treatment strategies for their patients.

Synonyms
(S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropionic acid monohydrate
CAS Number
38821-49-7
Purity
≥ 98% (Assay, HPLC)
Molecular Formula
C10H14N2O4·H2O
Molecular Weight
244.25
MDL Number
MFCD00889211
PubChem ID
441291
Appearance
White to light yellow powder to crystaline
Optical Rotation
[a]20D = -21.0 to -23.5 ° (C=1 in AlCl3 sol.)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropionic acid monohydrate
CAS Number
38821-49-7
Purity
≥ 98% (Assay, HPLC)
Molecular Formula
C10H14N2O4·H2O
Molecular Weight
244.25
MDL Number
MFCD00889211
PubChem ID
441291
Appearance
White to light yellow powder to crystaline
Optical Rotation
[a]20D = -21.0 to -23.5 ° (C=1 in AlCl3 sol.)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Carbidopa monohydrate is widely utilized in research focused on:

  • Parkinson's Disease Treatment: It is a key component in medications that help manage symptoms of Parkinson's disease by preventing the conversion of levodopa to dopamine outside the brain, enhancing its effectiveness.
  • Pharmaceutical Formulations: Used in combination with levodopa, it improves the bioavailability of the drug, allowing for lower doses and reduced side effects, making treatments more tolerable for patients.
  • Research on Neurotransmitter Regulation: Carbidopa monohydrate is employed in studies investigating the role of neurotransmitters in neurological disorders, providing insights into brain chemistry and potential new therapies.
  • Clinical Trials: It is frequently included in clinical trials aimed at developing new treatment protocols for movement disorders, helping to assess the efficacy and safety of new drug combinations.
  • Patient Compliance Improvement: By reducing the side effects associated with levodopa therapy, it enhances patient adherence to treatment regimens, which is crucial for managing chronic conditions effectively.

Citations