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Catalog Number:
37735
CAS Number:
2030-63-9
Clofazimine
Purity:
≥ 98% (HPLC)
Synonym(s):
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropylimino)phenazin-2-amine
Documents
$65.40 /1G
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Product Information

Clofazimine is a potent phenazine derivative primarily recognized for its therapeutic applications in the treatment of leprosy and certain types of mycobacterial infections. This compound exhibits unique properties, including anti-inflammatory and antimicrobial effects, making it invaluable in both clinical and research settings. Its mechanism of action involves the inhibition of mycobacterial growth, which is crucial for managing chronic infections. Researchers and healthcare professionals appreciate Clofazimine for its ability to enhance the efficacy of other antitubercular agents, thereby improving treatment outcomes for patients with multidrug-resistant tuberculosis.

In addition to its established use in infectious disease treatment, Clofazimine is being explored for potential applications in oncology due to its ability to induce apoptosis in cancer cells. This versatility positions Clofazimine as a compound of interest for ongoing studies aimed at expanding its therapeutic scope. With its proven track record and emerging applications, Clofazimine stands out as a critical tool for researchers and healthcare providers seeking effective solutions in challenging medical scenarios.

Synonyms
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropylimino)phenazin-2-amine
CAS Number
2030-63-9
Purity
≥ 98% (HPLC)
Molecular Formula
C27H22Cl2N4
Molecular Weight
473.4
MDL Number
MFCD00056793
PubChem ID
2794
Melting Point
219 °C (Lit.)
Appearance
Orange to red to brown powder or crystals
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropylimino)phenazin-2-amine
CAS Number
2030-63-9
Purity
≥ 98% (HPLC)
Molecular Formula
C27H22Cl2N4
Molecular Weight
473.4
MDL Number
MFCD00056793
PubChem ID
2794
Melting Point
219 °C (Lit.)
Appearance
Orange to red to brown powder or crystals
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Clofazimine is widely utilized in research focused on:

  • Leprosy Treatment: Primarily used as an antibiotic in the treatment of leprosy, it helps to reduce the bacterial load and alleviate symptoms, making it essential in dermatology and infectious disease management.
  • Multidrug-Resistant Tuberculosis: It is effective against multidrug-resistant strains of tuberculosis, providing a critical option for patients who do not respond to standard therapies.
  • Anti-Inflammatory Applications: Research indicates that clofazimine possesses anti-inflammatory properties, which can be beneficial in treating chronic inflammatory conditions, offering a dual action in certain therapeutic regimens.
  • Research in Cancer: Emerging studies suggest potential applications in oncology, where clofazimine may inhibit tumor growth, making it a candidate for further investigation in cancer treatments.
  • Veterinary Medicine: It is also used in veterinary practices for treating certain infections in animals, showcasing its versatility across different fields of medicine.

Citations