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Catalog Number:
37784
CAS Number:
78628-80-5
Terbinafine hydrochloride
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine hydrochloride, (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride
Documents
$133.30 /1G
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Product Information

Terbinafine hydrochloride is a potent antifungal agent widely utilized in the treatment of various dermatophyte infections, including athlete's foot, ringworm, and nail fungus. This compound works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby effectively disrupting fungal growth and reproduction. Its high lipophilicity allows for excellent tissue penetration, making it particularly effective for topical applications and systemic treatments. Researchers and healthcare professionals appreciate its rapid action and favorable safety profile, which contribute to its popularity in both clinical and pharmaceutical settings.

In addition to its therapeutic applications, terbinafine hydrochloride has been explored for its potential in veterinary medicine and as a research tool in studying fungal biology. Its unique mechanism of action distinguishes it from other antifungal agents, providing a valuable option for patients who may not respond to traditional treatments. With its proven efficacy and versatility, terbinafine hydrochloride remains a critical compound in the fight against fungal infections.

Synonyms
trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine hydrochloride, (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride
CAS Number
78628-80-5
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C21H25N·HCl
Molecular Weight
327.9
MDL Number
MFCD00145430
PubChem ID
64146
Melting Point
214 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine hydrochloride, (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride
CAS Number
78628-80-5
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C21H25N·HCl
Molecular Weight
327.9
MDL Number
MFCD00145430
PubChem ID
64146
Melting Point
214 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Terbinafine hydrochloride is widely utilized in research focused on

  • Antifungal Treatments: Commonly used in dermatology, it effectively treats fungal infections like athlete's foot and nail fungus, providing quick relief and promoting healing.
  • Pharmaceutical Development: Serves as a key compound in the formulation of topical and oral antifungal medications, making it essential for pharmaceutical companies aiming to develop effective treatments.
  • Veterinary Medicine: Employed in treating fungal infections in animals, ensuring that pets and livestock receive effective care, which is crucial for animal health and welfare.
  • Research on Drug Resistance: Used in studies investigating antifungal resistance mechanisms, helping researchers understand how fungi adapt and develop resistance to treatments.
  • Cosmetic Applications: Incorporated into certain skincare products aimed at preventing fungal infections, providing an added benefit for consumers looking for protective skincare solutions.

Citations