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Catalog Number:
37812
CAS Number:
130693-82-2
Dorzolamide hydrochloride
Purity:
≥ 98% (Assay by titration, HPLC)
Documents
$265.90 /200MG
Pack Size Availability Price
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Product Information

Dorzolamide hydrochloride is a potent carbonic anhydrase inhibitor primarily used in the treatment of elevated intraocular pressure in conditions such as glaucoma and ocular hypertension. This compound works by reducing the production of aqueous humor, thereby lowering intraocular pressure and helping to prevent vision loss. Its unique structure allows for effective penetration into ocular tissues, making it a preferred choice for topical ophthalmic formulations.

In addition to its primary use in ophthalmology, Dorzolamide hydrochloride has potential applications in various research settings, including studies focused on metabolic disorders and other conditions where carbonic anhydrase activity plays a critical role. Researchers appreciate its specificity and efficacy, which can lead to improved patient outcomes in clinical settings. With its established safety profile and effectiveness, Dorzolamide hydrochloride remains a valuable compound for both healthcare professionals and researchers alike.

CAS Number
130693-82-2
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C10H16N2O4S3·HCl
Molecular Weight
360.89
MDL Number
MFCD00884659
PubChem ID
9863722
Melting Point
281 °C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -7 to -9 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
General Information
CAS Number
130693-82-2
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C10H16N2O4S3·HCl
Molecular Weight
360.89
MDL Number
MFCD00884659
PubChem ID
9863722
Melting Point
281 °C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -7 to -9 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Dorzolamide hydrochloride is widely utilized in research focused on:

  • Glaucoma Treatment: This compound is primarily used as an eye drop medication to reduce intraocular pressure in patients with open-angle glaucoma or ocular hypertension, providing a non-invasive treatment option.
  • Carbonic Anhydrase Inhibition: It serves as a valuable tool in pharmacological studies to investigate the role of carbonic anhydrase enzymes in various physiological and pathological processes, aiding researchers in drug development.
  • Combination Therapies: Often used in conjunction with other medications, it enhances the efficacy of treatments for eye conditions, allowing for lower dosages of other drugs and minimizing side effects.
  • Research in Neurology: Investigations into its potential neuroprotective effects are ongoing, particularly in conditions like Alzheimer’s disease, where it may help in managing symptoms.
  • Formulation Development: The compound is utilized in the development of innovative drug delivery systems, improving the stability and bioavailability of therapeutic agents.

Citations