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Catalog Number:
38467
CAS Number:
130622-05-8
Boc-D-glutamic acid dimethyl ester
Purity:
≥ 96% (HPLC)
Synonym(s):
(R)-N-Boc-glutamic acid 1,5-dimethyl ester, Boc-D-Glu(OMe)-OMe
Documents
$43.87 /250MG
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Product Information

Boc-D-glutamic acid dimethyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This protected form of D-glutamic acid serves as a crucial building block in the development of bioactive peptides and pharmaceuticals, allowing for the selective modification of amino acids. Its unique Boc (tert-butyloxycarbonyl) protecting group enhances stability during synthesis, making it an ideal choice for researchers aiming to create complex peptide structures with improved efficacy and specificity.

In addition to its applications in peptide synthesis, Boc-D-glutamic acid dimethyl ester is also valuable in the study of neuroactive compounds and drug delivery systems. Its ability to facilitate the introduction of functional groups allows for the exploration of new therapeutic agents targeting various biological pathways. Researchers appreciate its ease of use and compatibility with standard coupling reagents, which streamlines the synthesis process. This compound not only enhances the efficiency of peptide synthesis but also opens avenues for innovative research in medicinal chemistry and drug development.

Synonyms
(R)-N-Boc-glutamic acid 1,5-dimethyl ester, Boc-D-Glu(OMe)-OMe
CAS Number
130622-05-8
Purity
≥ 96% (HPLC)
Molecular Formula
C12H21NO6
Molecular Weight
275.3
MDL Number
MFCD03094773
PubChem ID
12180112
Appearance
Light yellowish oil
Optical Rotation
[a]20D = 22 ± 0.5 ° (C=1 in EtOH)
Conditions
Store at 0-8°C
General Information
Synonyms
(R)-N-Boc-glutamic acid 1,5-dimethyl ester, Boc-D-Glu(OMe)-OMe
CAS Number
130622-05-8
Purity
≥ 96% (HPLC)
Molecular Formula
C12H21NO6
Molecular Weight
275.3
MDL Number
MFCD03094773
PubChem ID
12180112
Appearance
Light yellowish oil
Optical Rotation
[a]20D = 22 ± 0.5 ° (C=1 in EtOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-glutamic acid dimethyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the pharmaceutical industry, where it helps create biologically active molecules.
  • Drug Development: Its role in modifying amino acids allows researchers to develop new drugs with enhanced efficacy and reduced side effects, making it valuable in medicinal chemistry.
  • Bioconjugation: The compound is used in bioconjugation processes to attach drugs or imaging agents to biomolecules, facilitating targeted therapy in cancer treatment.
  • Research in Neuroscience: It aids in studying neurotransmitter pathways by acting as a precursor for glutamate derivatives, which are crucial for understanding brain function.
  • Polymer Chemistry: Boc-D-glutamic acid dimethyl ester is employed in the synthesis of biodegradable polymers, contributing to advancements in sustainable materials for various applications.

Citations