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Catalog Number:
43369
CAS Number:
301673-16-5
1-(tert-Butoxycarbonyl)-3-(hydroxymethyl)piperazine
Purity:
≥ 98% (GC)
Synonym(s):
1-Boc-3-(hydroxymethyl)piperazine, tert-Butyl 3-(Hydroxymethyl)piperazine-1-carboxylate, 3-(Hydroxymethyl)piperazine-1-carboxylic acid tert-butyl ester
Documents
$225.24 /200MG
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Product Information

1-(tert-Butoxycarbonyl)-3-(hydroxymethyl)piperazine is a versatile compound widely utilized in the fields of medicinal chemistry and pharmaceuticals. This compound serves as a key intermediate in the synthesis of various bioactive molecules, particularly in the development of piperazine derivatives that exhibit significant pharmacological activities. Its unique structure, featuring a tert-butoxycarbonyl protecting group, allows for selective functionalization, making it an essential building block in complex organic synthesis. Researchers appreciate its stability and ease of handling, which facilitate the efficient production of compounds with potential therapeutic applications.

In addition to its role in drug development, 1-(tert-Butoxycarbonyl)-3-(hydroxymethyl)piperazine is also valuable in the preparation of peptide-based therapeutics and can be employed in the synthesis of ligands for various biological targets. Its ability to enhance solubility and bioavailability of active pharmaceutical ingredients positions it as a preferred choice among professionals seeking to optimize drug formulations. With its broad applicability and advantageous properties, this compound is an essential resource for researchers and industry professionals aiming to innovate in drug discovery and development.

Synonyms
1-Boc-3-(hydroxymethyl)piperazine, tert-Butyl 3-(Hydroxymethyl)piperazine-1-carboxylate, 3-(Hydroxymethyl)piperazine-1-carboxylic acid tert-butyl ester
CAS Number
301673-16-5
Purity
≥ 98% (GC)
Molecular Formula
C10H20N2O3
Molecular Weight
216.28
MDL Number
MFCD04115304
PubChem ID
22386508
Melting Point
93 - 97 °C
Appearance
White to almost white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-Boc-3-(hydroxymethyl)piperazine, tert-Butyl 3-(Hydroxymethyl)piperazine-1-carboxylate, 3-(Hydroxymethyl)piperazine-1-carboxylic acid tert-butyl ester
CAS Number
301673-16-5
Purity
≥ 98% (GC)
Molecular Formula
C10H20N2O3
Molecular Weight
216.28
MDL Number
MFCD04115304
PubChem ID
22386508
Melting Point
93 - 97 °C
Appearance
White to almost white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1-(tert-Butoxycarbonyl)-3-(hydroxymethyl)piperazine is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of piperazine derivatives that exhibit biological activity.
  • Peptide Synthesis: It is commonly used in solid-phase peptide synthesis, where its protective group allows for selective reactions, enhancing the efficiency of peptide assembly.
  • Drug Formulation: The compound can be incorporated into drug formulations to improve solubility and stability, making it beneficial in the design of oral medications.
  • Research in Neuroscience: Its structural properties enable it to be a valuable tool in studying neurotransmitter systems, aiding researchers in understanding neurological pathways.
  • Bioconjugation Techniques: The compound is useful in bioconjugation processes, allowing for the attachment of biomolecules to surfaces or other molecules, which is essential in developing targeted therapies.

Citations