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Catalog Number:
43415
CAS Number:
118811-07-7
1-(tert-Butoxycarbonyl)-4-(p-toluenesulfonyloxy)piperidine
Purity:
≥ 98% (HPLC)
Synonym(s):
1-Boc-4-tosyloxypiperidine, 1-Boc-4-piperidyl p-toluenesulfonate, 4-(p-Toluenesulfonyloxy)piperidine-1-carboxylic acid tert-butyl ester, tert-Butyl 4-tosyloxypiperidine-1-carboxylate
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$50.78 /1G
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Product Information

1-(tert-Butoxycarbonyl)-4-(p-toluenesulfonyloxy)piperidine is a versatile compound widely utilized in organic synthesis and pharmaceutical development. This compound, also known as tert-butyl 4-(4-methylphenyl)sulfonyloxypiperidine-1-carboxylate, features a unique structure that enhances its reactivity and selectivity in various chemical reactions. Its sulfonate group contributes to its effectiveness as a leaving group, making it an ideal candidate for nucleophilic substitution reactions. Researchers and industry professionals appreciate its application in the synthesis of complex molecules, particularly in the development of pharmaceuticals and agrochemicals.

The compound's stability and solubility in organic solvents further enhance its utility in laboratory settings. It is particularly valuable in the synthesis of piperidine derivatives, which are crucial in the production of various therapeutic agents. Additionally, its ability to facilitate the formation of carbon-nitrogen bonds makes it a key player in the development of new drug candidates. With its favorable properties and broad applicability, 1-(tert-Butoxycarbonyl)-4-(p-toluenesulfonyloxy)piperidine stands out as a valuable tool for researchers aiming to innovate in the fields of medicinal chemistry and synthetic organic chemistry.

Synonyms
1-Boc-4-tosyloxypiperidine, 1-Boc-4-piperidyl p-toluenesulfonate, 4-(p-Toluenesulfonyloxy)piperidine-1-carboxylic acid tert-butyl ester, tert-Butyl 4-tosyloxypiperidine-1-carboxylate
CAS Number
118811-07-7
Purity
≥ 98% (HPLC)
Molecular Formula
C17H25NO5S
Molecular Weight
355.45
MDL Number
MFCD06796535
PubChem ID
15734713
Melting Point
96 - 100 °C
Appearance
White to almost white crystalline powder
Conditions
Store at RT
General Information
Synonyms
1-Boc-4-tosyloxypiperidine, 1-Boc-4-piperidyl p-toluenesulfonate, 4-(p-Toluenesulfonyloxy)piperidine-1-carboxylic acid tert-butyl ester, tert-Butyl 4-tosyloxypiperidine-1-carboxylate
CAS Number
118811-07-7
Purity
≥ 98% (HPLC)
Molecular Formula
C17H25NO5S
Molecular Weight
355.45
MDL Number
MFCD06796535
PubChem ID
15734713
Melting Point
96 - 100 °C
Appearance
White to almost white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1-(tert-Butoxycarbonyl)-4-(p-toluenesulfonyloxy)piperidine is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of piperidine-based drugs, which are known for their efficacy in treating neurological disorders.
  • Organic Synthesis: It is a valuable reagent in organic chemistry for constructing complex molecular architectures, allowing chemists to create diverse compounds with tailored properties.
  • Material Science: This chemical can be used in the formulation of advanced materials, contributing to the development of polymers and coatings that require specific functional groups for enhanced performance.
  • Biochemical Research: Researchers utilize this compound in the study of enzyme inhibitors and receptor interactions, aiding in the discovery of new therapeutic agents.
  • Analytical Chemistry: It is employed as a standard in various analytical methods, helping to calibrate instruments and validate results in quantitative analyses.

Citations