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Catalog Number:
43447
CAS Number:
75844-69-8
1-(tert-Butoxycarbonyl)piperidine
Purity:
≥ 98% (GC)
Synonym(s):
1-Boc-piperidine, tert-Butyl piperidine-1-carboxylate, Piperidine-1-carboxylic acid tert-butyl ester
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$67.70 /5G
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Product Information

1-(tert-Butoxycarbonyl)piperidine is a versatile chemical compound widely utilized in organic synthesis and pharmaceutical research. This compound serves as a protective group for amines, allowing for selective reactions in complex organic molecules. Its stability and ease of removal make it an ideal choice for researchers looking to streamline their synthetic pathways. In the pharmaceutical industry, it plays a crucial role in the development of various bioactive compounds, particularly in the synthesis of piperidine derivatives that exhibit significant biological activity.

The unique properties of 1-(tert-Butoxycarbonyl)piperidine, such as its ability to enhance solubility and improve the stability of reactive intermediates, make it a valuable asset in drug discovery and development. Researchers can leverage its protective capabilities to facilitate the synthesis of complex molecules while minimizing side reactions. This compound is particularly beneficial in the production of novel therapeutic agents, where precision and efficiency are paramount. Its application in the synthesis of piperidine-based pharmaceuticals highlights its importance in advancing medicinal chemistry.

Synonyms
1-Boc-piperidine, tert-Butyl piperidine-1-carboxylate, Piperidine-1-carboxylic acid tert-butyl ester
CAS Number
75844-69-8
Purity
≥ 98% (GC)
Molecular Formula
C10H19NO2
Molecular Weight
185.27
MDL Number
MFCD02093935
PubChem ID
7010304
Density
0.96
Appearance
Colorless to almost clear liquid
Boiling Point
120 °C/2 mmHg
Refractive Index
n20D 1.46
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-Boc-piperidine, tert-Butyl piperidine-1-carboxylate, Piperidine-1-carboxylic acid tert-butyl ester
CAS Number
75844-69-8
Purity
≥ 98% (GC)
Molecular Formula
C10H19NO2
Molecular Weight
185.27
MDL Number
MFCD02093935
PubChem ID
7010304
Density
0.96
Appearance
Colorless to almost clear liquid
Boiling Point
120 °C/2 mmHg
Refractive Index
n20D 1.46
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1-(tert-Butoxycarbonyl)piperidine is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: This compound serves as an important intermediate in the synthesis of various pharmaceutical agents, particularly those targeting neurological disorders. Its ability to enhance solubility and bioavailability makes it a valuable building block.
  • Peptide Chemistry: In peptide synthesis, it acts as a protective group for amines, allowing for selective reactions. This application is crucial in developing peptide-based drugs and biologics.
  • Organic Synthesis: It is frequently used in organic synthesis as a versatile reagent, facilitating the formation of complex molecules. Researchers benefit from its ability to streamline multi-step reactions.
  • Material Science: The compound is explored in the development of new materials, particularly in creating polymers with specific properties. Its incorporation can lead to enhanced mechanical strength and thermal stability.
  • Research and Development: In academic and industrial research settings, it is employed in the exploration of new chemical reactions and methodologies, contributing to advancements in synthetic chemistry.

Citations