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Catalog Number:
46458
CAS Number:
17763-67-6
Phenyl trifluoromethanesulfonate
Purity:
≥ 98% (GC)
Synonym(s):
Trifluoromethanesulfonic acid phenyl ester, Phenyl triflate
Hazmat
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$35.90 /1G
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Product Information

Phenyl trifluoromethanesulfonate is a versatile reagent widely utilized in organic synthesis, particularly in the field of medicinal chemistry. This compound serves as an effective electrophilic fluorinating agent, enabling the introduction of trifluoromethyl groups into various organic substrates. Its unique trifluoromethanesulfonate moiety enhances reactivity, making it an invaluable tool for researchers looking to develop novel fluorinated compounds with potential pharmaceutical applications.

In addition to its role in fluorination, Phenyl trifluoromethanesulfonate is also employed in the synthesis of complex molecules, including agrochemicals and specialty chemicals. Its ability to facilitate the formation of carbon-fluorine bonds is particularly advantageous in the development of compounds with enhanced biological activity and stability. Researchers and industry professionals can leverage this compound to streamline their synthesis processes, improve yields, and explore new avenues in drug discovery and material science.

Synonyms
Trifluoromethanesulfonic acid phenyl ester, Phenyl triflate
CAS Number
17763-67-6
Purity
≥ 98% (GC)
Molecular Formula
C7H5F3O3S
Molecular Weight
226.17
MDL Number
MFCD00192399
PubChem ID
548641
Density
1.41
Appearance
Colorless to almost colorless clear liquid
Boiling Point
62 °C/13 mmHg
Refractive Index
n20D 1.43
Conditions
Store at RT
General Information
Synonyms
Trifluoromethanesulfonic acid phenyl ester, Phenyl triflate
CAS Number
17763-67-6
Purity
≥ 98% (GC)
Molecular Formula
C7H5F3O3S
Molecular Weight
226.17
MDL Number
MFCD00192399
PubChem ID
548641
Density
1.41
Appearance
Colorless to almost colorless clear liquid
Boiling Point
62 °C/13 mmHg
Refractive Index
n20D 1.43
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Phenyl trifluoromethanesulfonate is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a powerful electrophilic reagent in the synthesis of various organic compounds, enabling chemists to efficiently introduce trifluoromethanesulfonyl groups into target molecules.
  • Pharmaceutical Development: It plays a crucial role in the pharmaceutical industry for the development of new drugs, particularly in the modification of existing drug molecules to enhance their efficacy and stability.
  • Polymer Chemistry: Used in the production of specialty polymers, it helps improve the thermal and chemical resistance of materials, making it valuable in industries such as automotive and electronics.
  • Fluorination Reactions: This compound is a key reagent in fluorination processes, allowing for the introduction of fluorine into organic molecules, which can significantly alter their properties and increase their bioactivity.
  • Analytical Chemistry: It is employed in the preparation of derivatives for analytical techniques, enhancing the detection and quantification of various compounds in complex mixtures.

Citations